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because a neuroendocrine tumor arises from cells that produce hormones the tumor can also produce hormones neuroendocrine tumors can develop anywhere in the body but most occur in the digestive tract pancreas rectum lungs or appendix they can be noncancerous benign or cancerous malignant, overview neuroendocrine tumors can be noncancerous benign or cancerous malignant diagnosis and treatment of neuroendocrine tumors depend on the type of tumor its location whether it produces excess hormones how aggressive it is and whether it has spread to other parts of the body